The promise of regenerative medicine to treat chronic pain

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There is tremendous potential in using regenerative medicine to relieve chronic pain, and the evidence for this practice is growing, said Alexios Carayannopoulos, DO, MPH, DABPMR, director of physical medicine and rehabilitation departments at Rhode Island Hospital and Newport Hospital, director of the Physical Medicine and Rehabilitation Department of the Lifespan Physician Group and Associate Professor at Brown University Warren Alpert Medical School.

Carayannopoulos will have a session on November 19th on “Regenerative Medicine: What Has Worked and Where is the Evidence?” moderate. during the American Society of Regional Anesthesia and Pain Medicine’s 20th Annual Pain Medicine Meeting in San Francisco and virtually.

Regenerative medicine “keeps stepping out of the lab,” he said, adding that he would like the session to “provide a broader understanding and appreciation of the theory behind regenerative medicine and its promising uses in pain management.” Research on animal models and evidence from limited, FDA-cleared human uses – such as the use of stem cells – make it clear that the field is wide open.

Regenerative medicine is the replacement, repair, or regrowth of damaged cells, tissues, or organs. For example, current animal research examines the effectiveness of regenerative medicine in treating pain associated with osteoarthritis and diabetic peripheral neuropathy, among others. Research is also being conducted into evidence that injecting certain types of stem cells into people with spinal cord injuries and degenerative disc disease may have an analgesic effect on severely debilitating nerve or neuropathic pain, as well as on skeletal or nociceptive pain. Carayannopoulos said the spinal injury results, when confirmed in human studies, raise the specter of using more aggressive rehabilitation to treat such injuries.

Regenerative medicine applications are slowly becoming commercially viable, but it is an unregulated industry with a long and costly route to US Food and Drug Administration approval. In addition, insurers typically do not adopt regenerative medicine applications, which makes them inaccessible to most patients.

Despite these hurdles, Carayannopoulos said the practice is having such a huge impact on pain management that it could transform medical practice and even the length of healthy human lives.

“Most of the things we do in pain management are palliative. Regenerative medicine is potentially restorative in nature and has an impact on population dynamics due to its preventive medical potential, ”he said. “There are many uses for regenerative medicine in pain management, and one of the benefits is that, in theory, you could turn the timer back on. It has the potential to have a huge impact on health care and the cost of providing it by limiting unnecessary potential.” Procedures and Operations. “

The session of the meeting will also be attended by speakers who will address recent advances in the field, the evidence base, regulatory outlook and integration into a vendor’s practice.

Autologous fat injection for shoulder pain in wheelchair users with spinal cord injuries

More information:
Meeting:… ain-medicine-meeting

Provided by the American Society of Regional Anesthesia and Pain Medicine (ASRA)

Quote: The Pledge of Regenerative Medicine to Treat Chronic Pain (2021, September 15), accessed September 15, 2021 from

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