Clinically relevant translational research Despite recent developments of sophisticated and novel methods in preclinical research, there is still a deficiency of models that can reliably replicate patient groups sufficiently to…
Tag: BMC
Ethical and regulatory issues of stem cell-derived 3-dimensional organoid and tissue therapy for personalised regenerative medicine | BMC Medicine
Mansour AA, Gonçalves JT, Bloyd CW, Li H, Fernandes S, Quang D, et al. An in vivo model of functional and vascularized human brain organoids. Nat Biotechnol. 2018;36(5):432–41. Article CAS …
Obese visceral fat tissue inflammation: from protective to detrimental? | BMC Medicine
Chen L, Deng H, Cui H, Fang J, Zuo Z, Deng J, et al. Inflammatory responses and inflammation-associated diseases in organs. Oncotarget. 2018;9:7204. Article Google Scholar Medzhitov R. The spectrum…
Genomic epidemiology of Escherichia coli: antimicrobial resistance through a One Health lens in sympatric humans, livestock and peri-domestic wildlife in Nairobi, Kenya | BMC Medicine
Murray CJL, Ikuta KS, Sharara F, Swechinsky L, Robles Aguilar G, Gray A, et al. Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis. lancet Tang KL, Caffrey…
Plant-based dietary patterns defined by a priori indices and colorectal cancer risk by sex and race/ethnicity: the Multiethnic Cohort Study | BMC Medicine
study population The MEC is a population-based, prospective cohort study designed to investigate lifestyle and genetic factors related to cancer and other chronic diseases [15]. Participants were identified from the…
Intestinal gluconeogenesis is downregulated in pediatric patients with celiac disease | BMC Medicine
The present study shows that children with untreated CD have lower expression of genes involved in IGN in duodenal biopsies compared with children with a normal intestinal mucosa. Decreased expression…
Added flavors: potential contributors to body weight gain and obesity? | BMC Medicine
European Food Safety Authority. Food additives. https://www.efsa.europa.eu/en/topics/topic/food-additives. Accessed 15 Aug 2022. European Parlament, Council of the European Union. Regulation (EC) No 1334/2008 of the European Parliament and of the Council…
SIRPα antibody combined with oncolytic virus OH2 protects against tumours by activating innate immunity and reprogramming the tumour immune microenvironment | BMC Medicine
Cell line and oncolytic virus The CT26, MC38, 4T-1, and RAW264.7 cell lines were purchased from the National Infrastructure of Cell Line Resource (Beijing, China) and kept by our laboratory.…